Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782590 | 0.81 | TSHR (0.38) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL866236 | 0.79 | CA14 (0.37) | — | |
| SCHEMBL778096 | 0.77 | CA1 (0.42) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL28496313 | 0.75 | TSHR (0.55) | TSHRALDH1A1 | |
| Formaldehyde SCHEMBL27924107 | 0.72 | CA1 (0.39) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL10896761 | 0.70 | CA1 (0.37) | TSHRALDH1A1CA1CA2CA9 | |
| Methyl Alcohol SCHEMBL10924123 | 0.70 | CA1 (0.33) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL41548 | 0.69 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL4611124 | 0.69 | CA1 (0.41) | ALDH1A1CA1CA2CA9 | |
| SCHEMBL964196 | 0.69 | CA1 (0.36) | ALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10874686-B2 | Anthranilyl-adenosinemonosulfamate analogs and uses thereof | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190038656-A1 | ANTHRANILYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | Memorial Slooan-Kettering Cancer Center (US) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874686-B2 | Anthranilyl-adenosinemonosulfamate analogs and uses thereof | ATIC, SLC35B2, ADORA1 | TSHR 3317/4885ALDH1A1 625/4885CA1 2429/4885 |
| US-20190038656-A1 | ANTHRANILYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | ATIC, SLC35B2, ADORA1 | TSHR 3317/4885ALDH1A1 625/4885CA1 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.