Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268299 | 0.92 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL268727 | 0.92 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19043109 | 0.90 | THRB (0.62) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9555330 | 0.90 | THRB (0.62) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9167028 | 0.90 | THRB (0.62) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2848811 | 0.89 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14124611 | 0.89 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4937876 | 0.88 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL268440 | 0.86 | THRB (0.66) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12596293 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025398-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | WO | disclosed |