SCHEMBL20712929

SCHEMBL20712929

FC1CCN(C2CCNC2)C1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.44
CCNT1 O60563 1/20 0.32
CDK9 P50750 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24033707 1.00 HTR6 (0.44) HTR6CCNT1CDK9ARG1ARG2
Hydrochloric Acid SCHEMBL29134756 0.98 HTR6 (0.42) HTR6CCNT1CDK9ARG1ARG2
Hydrochloric Acid SCHEMBL34473706 0.98 HTR6 (0.42) HTR6CCNT1CDK9ARG1ARG2
SCHEMBL31209270 0.90 HTR6 (0.48) HTR6
SCHEMBL24672972 0.88 HTR6 (0.50) HTR6ARG1ARG2
SCHEMBL15363274 0.87 HTR6 (0.52) HTR6
SCHEMBL31209586 0.87 HTR6 (0.52) HTR6
SCHEMBL2372206 0.87 HPGD (0.34)
SCHEMBL2675204 0.87 HPGD (0.34)
SCHEMBL30814430 0.87 HTR6 (0.42) HTR6ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10654856-B2 Method for preparing pyrrolo[3,2-D]pyrimidine compound, and intermediates thereof CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2020-05-19 US disclosed
US-20190040072-A1 METHOD FOR PREPARING PYRROLO[3,2-D]PYRIMIDINE COMPOUND, AND INTERMEDIATES THEREOF CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2019-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040072-A1 METHOD FOR PREPARING PYRROLO[3,2-D]PYRIMIDINE COMPOUND, AND INTERMEDIATES THEREOF DPYD, TYMS, TYMP HTR6 2136/4885CCNT1 196/4885CDK9 50/4885
US-10654856-B2 Method for preparing pyrrolo[3,2-D]pyrimidine compound, and intermediates thereof DPYD, TYMS, TYMP HTR6 2136/4885CCNT1 196/4885CDK9 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.