Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20713774 | 0.81 | ACKR3 (0.44) | NAA50KLKB1 | |
| SCHEMBL22277237 | 0.79 | KLKB1 (0.44) | KLKB1 | |
| SCHEMBL20713642 | 0.76 | KLKB1 (0.40) | NAA50KLKB1 | |
| SCHEMBL20713881 | 0.75 | KLKB1 (0.38) | NAA50KLKB1 | |
| SCHEMBL20713771 | 0.74 | TRPC3 (0.42) | KLKB1 | |
| SCHEMBL20713634 | 0.74 | KLKB1 (0.43) | NAA50KLKB1 | |
| SCHEMBL22277258 | 0.73 | KLKB1 (0.66) | KLKB1 | |
| SCHEMBL22277246 | 0.73 | KLKB1 (0.67) | KLKB1 | |
| SCHEMBL22277264 | 0.72 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL15296758 | 0.71 | HIF1A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |