Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20713749 | 0.93 | KLKB1 (0.59) | KLKB1KLK1 | |
| SCHEMBL20705083 | 0.89 | KLKB1 (0.75) | KLKB1KLK1 | |
| SCHEMBL29393974 | 0.89 | KLKB1 (0.75) | KLKB1KLK1 | |
| SCHEMBL20713753 | 0.88 | KLKB1 (0.62) | KLKB1 | |
| SCHEMBL20713890 | 0.86 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL20713747 | 0.86 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL20713772 | 0.83 | KLKB1 (0.64) | KLKB1 | |
| SCHEMBL20705090 | 0.82 | KLKB1 (0.76) | KLKB1 | |
| SCHEMBL20705290 | 0.82 | KLKB1 (0.76) | KLKB1 | |
| SCHEMBL29391737 | 0.82 | KLKB1 (0.76) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |