Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23380634 | 0.96 | KDM4E (0.37) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL23380635 | 0.96 | KDM4E (0.37) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL20030271 | 0.95 | ALDH1A1 (0.38) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL20030032 | 0.95 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL20024223 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL22006918 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL17087617 | 0.94 | TSHR (0.41) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL20029899 | 0.94 | ALDH1A1 (0.39) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL23380241 | 0.93 | KDM4E (0.38) | ALDH1A1TSHRHPGDMAPTKDM4E | |
| SCHEMBL24388280 | 0.93 | PIM1 (0.39) | ALDH1A1TSHRHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190044071-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190044071-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | BRD3, BRPF3, DDT | ALDH1A1 610/4885TSHR 3778/4885HPGD 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.