Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20716034 | 0.77 | KDM1A (0.49) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6546517 | 0.76 | MAPT (0.72) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL20716075 | 0.76 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL25804366 | 0.76 | ALDH1A1 (0.72) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL20716031 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EPTGS2KMT2A | |
| SCHEMBL20703324 | 0.74 | MAPT (0.65) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL20716011 | 0.74 | MAPT (0.45) | MAPTALDH1A1KDM4EHTTPTGS2 | |
| SCHEMBL9547985 | 0.73 | MAPT (0.68) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9548090 | 0.73 | MAPT (0.68) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL8068531 | 0.73 | ALDH1A1 (0.68) | MAPTALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028104-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ALPHALA CO., LTD. (TW) | 2019-02-07 | — | — | WO | disclosed |