Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20717974 | 1.00 | EPHX1 (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20704313 | 0.98 | EPHX1 (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20704314 | 0.98 | EPHX1 (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL1337302 | 0.84 | ALPI (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL859558 | 0.84 | ALPI (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL1256892 | 0.84 | ALPI (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL8837447 | 0.83 | ALPI (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL10825611 | 0.77 | EPHX1 (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| L-Phenylalaninol SCHEMBL28108894 | 0.77 | EPHX1 (0.64) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL20704590 | 0.77 | CYP3A4 (0.47) | EPHX1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401401-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | HERCULES CAPITAL, INC. | 2022-12-22 | — | — | US | disclosed |
| US-20210093603-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2021-04-01 | — | — | US | disclosed |
| WO-2019027941-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED (BM) | 2019-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093603-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | DNPEP, CPS1, GLS | EPHX1 2559/4885ALPI 404/4885PKM 1029/4885 |
| US-20220401401-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | DNPEP, CPS1, GLS | EPHX1 2559/4885ALPI 404/4885PKM 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.