Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178402 | 0.93 | CYP2C19 (0.38) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL1711205 | 0.81 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL7857533 | 0.79 | — | — | |
| SCHEMBL11237533 | 0.79 | TSHR (0.37) | TSHRKMT2AMEN1 | |
| SCHEMBL28664926 | 0.77 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL30620386 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1 | |
| SCHEMBL30094966 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1 | |
| SCHEMBL23579190 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1 | |
| SCHEMBL2430576 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1 | |
| SCHEMBL28899886 | 0.77 | TSHR (0.42) | TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019024429-A1 | MOISTURE CURABLE COMPOSITIONS | DOW SILICONES CORPORATION (US) | 2019-02-07 | — | — | WO | disclosed |