Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730908 | 0.84 | EPHX1 (0.61) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL21065978 | 0.84 | EPHX1 (0.61) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL10005631 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL989960 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL7808628 | 0.79 | EPHX1 (0.67) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL19710825 | 0.79 | EPHX1 (0.67) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL10825611 | 0.78 | EPHX1 (0.53) | EPHX1ANPEPMMP2ALPIPKM | |
| SCHEMBL28656 | 0.78 | EPHX1 (1.00) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL21918912 | 0.78 | EPHX1 (0.64) | EPHX1ANPEPSLC6A2TAAR1MAOA | |
| SCHEMBL137074 | 0.76 | EPHX1 (0.76) | EPHX1ANPEPSLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027941-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED (BM) | 2019-02-07 | — | — | WO | disclosed |