Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730908 | 1.00 | EPHX1 (0.61) | EPHX1ANPEPSLC6A2TAAR1SLC6A4 | |
| SCHEMBL20717822 | 0.84 | EPHX1 (0.61) | EPHX1ANPEPSLC6A2TAAR1SLC6A4 | |
| SCHEMBL2549520 | 0.82 | EPHX1 (0.43) | EPHX1CYP2D6 | |
| SCHEMBL7114970 | 0.82 | EPHX1 (0.43) | EPHX1CYP2D6 | |
| SCHEMBL1168400 | 0.82 | EPHX1 (0.43) | EPHX1CYP2D6 | |
| SCHEMBL5683174 | 0.82 | ANPEP (0.57) | EPHX1ANPEP | |
| SCHEMBL10005631 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPSLC6A2TAAR1SLC6A4 | |
| SCHEMBL989960 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPSLC6A2TAAR1SLC6A4 | |
| SCHEMBL22013209 | 0.81 | EPHX1 (0.44) | EPHX1SLC6A2TAAR1SLC6A4MAOA | |
| Hydrochloric Acid SCHEMBL5681153 | 0.81 | ANPEP (0.55) | EPHX1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |