SCHEMBL20718

SCHEMBL20718

Nc1cc[nH]c(=S)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11114659 0.98
Pyrimidine SCHEMBL25195689 0.86 HSP90AA1 (0.33)
SCHEMBL546194 0.75
Cytosine SCHEMBL1330400 0.70
Cytosine SCHEMBL4059 0.70
Cytosine SCHEMBL4657334 0.70 DYRK1A (0.44)
Cytosine SCHEMBL1330710 0.70
SCHEMBL160947 0.70
Cytosine SCHEMBL19692377 0.68
Cytosine SCHEMBL4492966 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 39115 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-12552858-B2 Methods and compositions for delivering mRNA coded antibodies TRANSLATE BIO, INC. (US) 2026-02-17 US claimed
EP-4659246-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES Atlas Data Storage, Inc. (US) 2025-12-10 EP claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed
US-5891684-A RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-04-06 US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
WO-1998039334-A9 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO 1999-02-18 WO claimed
WO-1998039334-A1 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-11 WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 US claimed
US-5126439-A Complementary purines and pyrimidines TEMPLE UNIVERSITY (US) 1992-06-30 US claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
EP-0483426-A1 Thiol heterocyclic deodorant composition and method of deodorization THE PROCTER & GAMBLE COMPANY (US) 1992-05-06 EP claimed