Cytosine

Cytosine

SCHEMBL4657334

Nc1cc[nH]c(=O)n1.Nc1cc[nH]c(=O)n1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DYRK1A Q13627 1/20 0.44
▸ TSHR P16473 1/20 0.36
▸ JAK2 O60674 1/20 0.36
▸ RPS6KA3 P51812 1/20 0.36
▸ MELK Q14680 1/20 0.36
▸ STK24 Q9Y6E0 1/20 0.36
▸ ADORA2A P29274 4/20 0.36
▸ ADORA1 P30542 4/20 0.36
▸ AURKA O14965 1/20 0.34
▸ AURKB Q96GD4 1/20 0.34
▸ INCENP Q9NQS7 1/20 0.34
▸ MAPT P10636 2/20 0.34
▸ PARP1 P09874 3/20 0.33
▸ RECQL P46063 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ ELANE P08246 1/20 0.32
▸ AXL P30530 1/20 0.32
▸ NUDT1 P36639 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytosine SCHEMBL4059 1.00 — —
Cytosine SCHEMBL1330400 1.00 — —
Cytosine SCHEMBL1330710 1.00 — —
Cytosine SCHEMBL2406920 0.98 — —
Cytosine SCHEMBL4065266 0.98 — —
Cytosine SCHEMBL10623341 0.98 — —
Cytosine SCHEMBL3678961 0.98 — —
Cytosine SCHEMBL20212017 0.98 — —
Cytosine SCHEMBL21772310 0.98 DYRK1A (0.42) DYRK1ATSHRJAK2RPS6KA3MELK
Cytosine SCHEMBL4492966 0.98 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229151-A9 COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY HARBINGER HEALTH, INC. 2024-07-11 — — US disclosed
CN-118098345-A Chromosome aneuploidy detection method, device, equipment and storage medium 深圳市真迈生物科技有限公司 2024-05-28 — — CN disclosed
US-20240132970-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2024-04-25 — — US disclosed
WO-2023147568-A2 COMPOSITIONS AND METHODS FOR MAKING AND USING AN IMMORTALIZED LIBRARY FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2023-08-03 — — WO disclosed
US-20230190709-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2023-06-22 — — US disclosed
CN-115340478-A Schiff base ligand and preparation method and application of polynuclear rare earth complex thereof 温州医科大学 2022-11-15 — — CN disclosed
CN-115266662-A Hyperspectral sequencing method and system and gene sequencer 深圳赛陆医疗科技有限公司 2022-11-01 — — CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 — — US disclosed
EP-3186231-A1 PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES University of Durham (GB) 2017-07-05 — — EP disclosed
CN-104316621-B Method for measuring total nucleotide in protein products 上海征泰饲料有限公司 2017-01-11 — — CN disclosed
CN-104520437-B A kind of chromosomal aneuploidy detection method and device 深圳华大基因股份有限公司 2016-09-14 — — CN disclosed
WO-2016030662-A1 PROCESS FOR PRODUCING FLUOROCYTOSINE AND FLUOROCYTOSINE DERIVATIVES UNIVERSITY OF DURHAM (GB) 2016-03-03 — — WO disclosed
CN-104043126-A Modulation of axon degeneration GENENTECH INC 2014-09-17 — — CN disclosed
CN-102573855-A Modulation of axonal degeneration HOFFMANN LA ROCHE 2012-07-11 — — CN disclosed
EP-1747276-B1 CAROTENOID BIOSYNTHESIS INHIBITOR RESISTANCE GENES AND METHODS OF USE IN PLANTS BASF PLANT SCIENCE GMBH (DE) 2008-12-10 — — EP disclosed
EP-1747276-A2 CAROTENOID BIOSYNTHESIS INHIBITOR RESISTANCE GENES AND METHODS OF USE IN PLANTS BASF Plant Science GmbH (DE) 2007-01-31 — — EP disclosed
WO-2005111218-A2 CAROTENOID BIOSYNTHESIS INHIBITOR RESISTANCE GENES AND METHODS OF USE IN PLANTS BASF PLANT SCIENCE GMBH (DE) 2005-11-24 — — WO disclosed
EP-1005478-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME Pitsch, Stefan (CH) 2000-06-07 — — EP disclosed
WO-1999009044-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME PITSCH STEFAN (CH) 1999-02-25 — — WO disclosed
US-5698583-A MIXING THE SOLUTION OF ATLEAST ONE OLIGOELEMENT, SELECTED FROM SODIUM SELENITE, MAGNESIUM /MANGANESE/AND ZINC CHLORIDE, COBALT, CERIUM, MOLYBDENUM AND SILICON WITH BUFFERED SOLUTION OF PHOSPHOLIPASE A2; USED FOR IMMUNOTHERAPY CRESCENTI ERNESTO J V (AR) 1997-12-16 — — US disclosed
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