Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288473 | 0.85 | CPA3 (0.62) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL5767750 | 0.85 | CPA3 (0.62) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL157500 | 0.85 | CPA3 (0.62) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL13452451 | 0.84 | EPHX1 (0.57) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL20717804 | 0.84 | EPHX1 (0.57) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL15638183 | 0.82 | ALPI (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20704531 | 0.82 | EPHX1 (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL20718005 | 0.82 | ALPI (0.56) | EPHX1ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL20704533 | 0.82 | EPHX1 (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL11473759 | 0.82 | EPHX1 (0.55) | EPHX1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027941-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | JAZZ PHARMACEUTICALS INTERNATIONAL III LIMITED (BM) | 2019-02-07 | — | — | WO | disclosed |