Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIPK2 | Q9H2X6 | 4/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464338 | 1.00 | HIPK2 (0.72) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL20704146 | 0.84 | HIPK2 (1.00) | HIPK2CSNK2A1 | |
| SCHEMBL1403704 | 0.82 | MRGPRX4 (0.56) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL113378 | 0.82 | SMYD3 (0.55) | HIPK2CSNK2A2CSNK2B | |
| SCHEMBL29489099 | 0.82 | SMYD3 (0.55) | HIPK2CSNK2A2CSNK2B | |
| SCHEMBL29488886 | 0.82 | MRGPRX4 (0.56) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL7088722 | 0.82 | PTPN1 (0.64) | PTPN1 | |
| SCHEMBL20704098 | 0.81 | HIPK2 (0.65) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL30771543 | 0.81 | HIPK2 (0.65) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 | |
| SCHEMBL6984075 | 0.81 | MRGPRX4 (0.55) | HIPK2CSNK2A2CSNK2BCSNK2A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028059-A1 | ANTI-CANCER/ANTI-FIBROSIS COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-07 | — | — | WO | disclosed |