Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489099 | 1.00 | SMYD3 (0.55) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL7557776 | 0.98 | SMYD3 (0.54) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| SCHEMBL29488886 | 0.92 | MRGPRX4 (0.56) | SMYD3MRGPRX4CYP3A4KDM4EHIPK2 | |
| SCHEMBL1403704 | 0.92 | MRGPRX4 (0.56) | SMYD3MRGPRX4CYP3A4KDM4EHIPK2 | |
| SCHEMBL6984075 | 0.91 | MRGPRX4 (0.55) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL29816771 | 0.91 | MRGPRX4 (0.55) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| Potassium SCHEMBL6984080 | 0.91 | MRGPRX4 (0.55) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| SCHEMBL9100347 | 0.90 | IMPDH2 (0.54) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| Imidazole SCHEMBL25324701 | 0.86 | SMYD3 (0.45) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E | |
| SCHEMBL27867058 | 0.84 | MRGPRX4 (0.50) | SMYD3MRGPRX4IMPDH2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065117-B1 | ISOQUINOLINE DERIVATIVES FOR USE IN TREATING GLUT1 DEFICIENCY SYNDROME | GLIAPHARM SA (CH) | 2024-06-19 | — | — | EP | claimed |
| CN-117286192-B | Use of amide synthetases in the preparation of litaxetil intermediates and/or litaxetil | 欣雅利华生物技术(上海)有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-117286192-A | Use of amide synthetases in the preparation of litaxetil intermediates and/or litaxetil | 欣雅利华生物技术(上海)有限公司 | 2023-12-26 | — | — | CN | claimed |
| US-20230374566-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-11-23 | — | — | US | claimed |
| EP-4217364-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | The Regents of the University of California (US) | 2023-08-02 | — | — | EP | claimed |
| WO-2022067036-A1 | METHODS OF IDENTIFYING PROTEIN BINDING SITES ON RNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-31 | — | — | WO | claimed |
| CN-111995575-A | Preparation method of quinoline amide compound | 河南农业大学 | 2020-11-27 | — | — | CN | claimed |
| CN-106831575-B | A kind of preparation method of 1- aminoisoquinoline -6- methanol | 北京六合宁远科技有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-107820496-A | For treating and preventing the hepatitis b virus infected new formic acid derivates of 4 oxo pyridine of Fourth Ring 3 | 豪夫迈·罗氏有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-106831575-A | A kind of preparation method of the methyl alcohol of 1 aminoisoquinoline 6 | 北京六合宁远科技有限公司 | 2017-06-13 | — | — | CN | claimed |
| EP-2424840-B1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-08-06 | — | — | EP | claimed |
| US-20100280028-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | US | claimed |
| WO-2010126811-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | WO | claimed |
| EP-1904449-A2 | INHIBITORS OF CHECKPOINT KINASES | Merck & Co., Inc. (US) | 2008-04-02 | — | — | EP | claimed |
| WO-2007008502-A2 | INHIBITORS OF CHECKPOINT KINASES | MERCK & CO., INC. (US) | 2007-01-18 | — | — | WO | claimed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| EP-0707656-B1 | BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS | BASF AG (DE) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280028-A1 | CXCR3 RECEPTOR ANTAGONISTS | CXCR3, CXCR1, CXCR2 | SMYD3 3862/4885MRGPRX4 29/4885IMPDH2 2109/4885 |
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | SMYD3 2472/4885MRGPRX4 453/4885IMPDH2 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.