Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19777750 | 0.85 | NPC1 (0.43) | NPC1SMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL29853528 | 0.84 | MAPT (0.43) | SMN1; SMN2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL20718828 | 0.84 | MAPT (0.43) | SMN1; SMN2KMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL14744412 | 0.82 | NPC1 (0.47) | NPC1SMN1; SMN2KMT2AGAAALDH1A1 | |
| SCHEMBL21342460 | 0.80 | KMT2A (0.44) | NPC1SMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL7214463 | 0.80 | NPC1 (0.45) | NPC1SMN1; SMN2KMT2AGAAALDH1A1 | |
| SCHEMBL29177211 | 0.77 | NPC1 (0.43) | NPC1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL2815023 | 0.77 | MAPT (0.51) | NPC1SMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL23412686 | 0.76 | KMT2A (0.41) | NPC1SMN1; SMN2KMT2AGAAMEN1 | |
| SCHEMBL14222278 | 0.75 | MAPT (0.46) | NPC1SMN1; SMN2KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441389-B1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA INC (CN) | 2021-09-08 | — | — | EP | disclosed |
| CN-109311865-B | Pyrazole-oxazolidinone compound for resisting hepatitis B virus | 上海挚盟医药科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA, INC. (CN) | 2019-05-23 | — | — | US | disclosed |
| EP-3441389-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | Shanghai Zhimeng Biopharma Co., Ltd (CN) | 2019-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | HAVCR2, ZC3HAV1, ZC3HAV1L | NPC1 2254/4885SMN1; SMN2 4730/4885KMT2A 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.