Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL20718902

C=CCCC=C.OCCOCCOCCOCCO

nearest known ligand 0.61

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
TSHR P16473 7/20 0.56
MAPK1 P28482 1/20 0.56
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 1/20 0.37
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11754046 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL2471478 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL10943454 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL6150504 0.92 MEN1 (0.58) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL10943449 0.89 TSHR (0.56) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL2470456 0.89
SCHEMBL6525668 0.87 MEN1 (0.52) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL27680359 0.86 TSHR (0.53) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL27597616 0.86 MEN1 (0.65) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL316812 0.85 TSHR (0.46) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3173826-B1 HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION PEGAVISION CORP (TW) 2019-02-13 EP claimed
CN-106967094-B The manufacturing method of hydrazine compound, the manufacturing method of optically anisotropic body and polymerizable compound 日本瑞翁株式会社 2019-11-15 CN disclosed
CN-105960392-B Polymerizable compound, polymerizable composition, polymerizable composition, macromolecule and optically anisotropic body 日本瑞翁株式会社 2018-06-22 CN disclosed
CN-106967094-A The manufacture method of hydrazine compound, the manufacture method of optically anisotropic body and polymerizable compound 日本瑞翁株式会社 2017-07-21 CN disclosed