Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330924 | 0.98 | — | — | |
| SCHEMBL6150801 | 0.91 | MEN1 (0.54) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL1468539 | 0.91 | MEN1 (0.54) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL826393 | 0.91 | MEN1 (0.54) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL2530379 | 0.91 | MEN1 (0.54) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL8897653 | 0.91 | TSHR (0.48) | MEN1KMT2ATSHRMAPK1MAPT | |
| Di(Hydroxyethyl)Ether SCHEMBL27680359 | 0.90 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL8898852 | 0.88 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL16589825 | 0.88 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1MAPT | |
| SCHEMBL823697 | 0.88 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299276-B2 | Interlocked molecules and related components, compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299276-B2 | Interlocked molecules and related components, compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8299276-B2 | Interlocked molecules and related components, compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2011-03-17 | — | — | US | disclosed |
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2011-03-17 | — | — | US | disclosed |
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065935-A1 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS | ECPAS, RAD52, ILK | MEN1 550/4885KMT2A 4822/4885TSHR 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.