2-Picolinic Acid

2-Picolinic Acid

SCHEMBL20721125

B.O=C(O)c1ccccn1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.95
▸ L3MBTL1 Q9Y468 2/20 0.95
▸ NAPRT Q6XQN6 1/20 0.95
▸ P4HTM Q9NXG6 1/20 0.95
▸ CES2 O00748 1/20 0.67
▸ CES1 P23141 1/20 0.67
▸ KMT2A Q03164 2/20 0.63
▸ ALDH1A1 P00352 3/20 0.61
▸ GSK3B P49841 1/20 0.55
▸ KDM4E B2RXH2 4/20 0.53
▸ NPC1 O15118 3/20 0.53
▸ RAB9A P51151 3/20 0.53
▸ MAPT P10636 2/20 0.53
▸ PKM P14618 2/20 0.53
▸ ALOX15 P16050 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ TSHR P16473 1/20 0.52
▸ ACMSD Q8TDX5 1/20 0.52
▸ PTGS2 P35354 1/20 0.50
▸ HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL29368665 0.98 — —
2-Picolinic Acid SCHEMBL28737810 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL7457912 0.98 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL36055 0.98 — —
2-Picolinic Acid SCHEMBL5058097 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5203401 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL673571 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL22835776 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL3732328 0.95 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250255920-A1 Controlled-Release and Stratified Cyclodextrin Inclusion Complex Vehicles CZAP RES AND DEVELOPMENT LLC (US) 2025-08-14 — — US disclosed
US-12285455-B2 Controlled-release and stratified cyclodextrin inclusion complex vehicles CZAP RESERACH AND DEVELOPMENT, LLC (US) 2025-04-29 — — US disclosed
CN-118234871-A Compositions and methods related to TET-assisted pyridine borane sequencing for cell free DNA 牛津大学校长、教师和学者 2024-06-21 — — CN disclosed
US-20230405074-A1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES CZAP RESEARCH AND DEVELOPMENT, LLC 2023-12-21 — — US disclosed
CN-116806266-A Method for detection of methylated base level in nucleic acids 豪夫迈·罗氏有限公司 2023-09-26 — — CN disclosed
EP-3892303-B1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES CZAP RES AND DEVELOPMENT LLC (US) 2023-06-07 — — EP disclosed
US-11633448-B2 Controlled-release and stratified cyclodextrin inclusion complex vehicles CZAP RESEARCH AND DEVELOPMENT LLC (US) 2023-04-25 — — US disclosed
EP-4098282-A1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES Czap Research And Development, LLC (US) 2022-12-07 — — EP disclosed
US-20220257690-A1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES CZAP RES AND DEVELOPMENT LLC (US) 2022-08-18 — — US disclosed
EP-3892303-A1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES Czap Research And Development, LLC (US) 2021-10-13 — — EP disclosed
EP-3411047-B1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES CZAP RES AND DEVELOPMENT LLC (US) 2021-04-14 — — EP disclosed
US-20190046598-A1 CONTROLLED-RELEASE AND STRATIFIED CYCLODEXTRIN INCLUSION COMPLEX VEHICLES CZAP RES AND DEVELOPMENT LLC (US) 2019-02-14 — — US disclosed
CN-108883125-A Controlled release and layered cyclodextrin inclusion complex vehicles 西泽普研究与发展有限责任公司 2018-11-23 — — CN disclosed
CN-102781519-B Boronic acid compositions 高露洁-棕榄公司 2018-02-23 — — CN disclosed
CN-103037867-A Borinic compositions COLGATE PALMOLIVE CO 2013-04-10 — — CN disclosed
CN-102781519-A Boronic acid compositions COLGATE PALMOLIVE CO 2012-11-14 — — CN disclosed
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