Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21686001 | 1.00 | RORC (0.39) | RORCPOLBL3MBTL1 | |
| SCHEMBL21684768 | 0.85 | MAPT (0.40) | RORCPOLBL3MBTL1 | |
| SCHEMBL20722715 | 0.85 | MAPT (0.40) | RORCPOLBL3MBTL1 | |
| SCHEMBL20722680 | 0.84 | PDK2 (0.42) | — | |
| SCHEMBL21685773 | 0.84 | PDK2 (0.42) | — | |
| SCHEMBL20722608 | 0.84 | MAPT (0.48) | — | |
| SCHEMBL20731008 | 0.84 | MAPT (0.48) | — | |
| SCHEMBL30061346 | 0.84 | MAPT (0.48) | — | |
| SCHEMBL20722742 | 0.81 | GRK2 (0.31) | POLBL3MBTL1 | |
| SCHEMBL20722745 | 0.81 | GRK2 (0.31) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3665169-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2020-06-17 | — | — | EP | disclosed |
| WO-2019032863-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | WO | disclosed |