SCHEMBL20723487

SCHEMBL20723487

NCCCC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.60
FOLH1 Q04609 1/20 0.58
DPP8 Q6V1X1 2/20 0.51
DPP9 Q86TI2 2/20 0.51
DPP7 Q9UHL4 2/20 0.51
CPB2 Q96IY4 6/20 0.48
GNAI3 P08754 1/20 0.47
GNAO1 P09471 1/20 0.47
GNAI1 P63096 1/20 0.47
SLC6A5 Q9Y345 1/20 0.46
NOD1 Q9Y239 1/20 0.46
DPP4 P27487 1/20 0.45
SLC15A2 Q16348 1/20 0.45
ERAP2 Q6P179 1/20 0.45
ERAP1 Q9NZ08 1/20 0.45
LNPEP Q9UIQ6 1/20 0.45
MMP2 P08253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20723484 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL30890373 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL1070057 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL30076247 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL8616589 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL1070055 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
SCHEMBL17696519 1.00 GSR (0.60) GSRFOLH1DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL4328805 0.98 GSR (0.58) GSRFOLH1DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL10439913 0.98 GSR (0.58) GSRFOLH1DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL1419587 0.98 GSR (0.58) GSRFOLH1DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-12492422-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment Sunbird Bio, Inc. (US) 2025-12-09 US disclosed
US-20250297300-A1 DETECTION, STAGING, MONITORING AND TREATING A DISEASE OR A CONDITION Sunbird Bio, Inc. 2025-09-25 US disclosed
US-20250223627-A1 FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE DETECTION IN BIOFLUIDS Sunbird Bio, Inc. 2025-07-10 US disclosed
US-20250215476-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR HEPATOCELLULAR CARCINOMA Sunbird Bio, Inc. 2025-07-03 US disclosed
US-20250197917-A1 METHOD OF PROTEASE DETECTION Sunbird Bio, Inc. 2025-06-19 US disclosed
US-12305217-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment Sunbird Bio, Inc. (US) 2025-05-20 US disclosed
US-20250110130-A1 EX VIVO PROTEASE ACTIVATION AND DETECTION Sunbird Bio, Inc. 2025-04-03 US disclosed
CN-119731239-A Iodinated crosslinked hydrogels and methods of forming the same 波士顿科学医学有限公司 2025-03-28 CN disclosed
CN-119731240-A Iodine labeled hydrogels and precursors thereof with improved properties 波士顿科学医学有限公司 2025-03-28 CN disclosed
US-11851697-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment GLYMPSE BIO, INC. (US) 2023-12-26 US disclosed
US-20230175037-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2023-06-08 US disclosed
US-11604193-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment GLYMPSE BIO, INC. (US) 2023-03-14 US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
WO-2022232124-A1 TARGETED ALPHA PARTICLE THERAPY FOR SOMATOSTATIN RECEPTOR 2 POSITIVE NEUROENDOCRINE TUMORS AND METASTASES H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2022-11-03 WO disclosed
US-20220178935-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-06-09 US disclosed
US-20220128567-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-04-28 US disclosed
US-20220128546-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-04-28 US disclosed
EP-3665161-A1 NEW TARGETED CYTOTOXIC RATJADONE DERIVATIVES AND CONJUGATES THEREOF Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2020-06-17 EP disclosed
WO-2019030284-A1 NEW TARGETED CYTOTOXIC RATJADONE DERIVATIVES AND CONJUGATES THEREOF Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2019-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP GSR 2913/4885FOLH1 48/4885DPP8 41/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD GSR 2920/4885FOLH1 21/4885DPP8 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.