Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725632 | 0.90 | BRAF (0.55) | BRAFKDR | |
| SCHEMBL20725656 | 0.89 | BRAF (0.53) | BRAFKDR | |
| SCHEMBL20725677 | 0.87 | BRAF (0.55) | BRAFKDR | |
| SCHEMBL20725644 | 0.85 | BRAF (0.56) | BRAFKDR | |
| SCHEMBL14979836 | 0.83 | BRAF (0.65) | BRAF | |
| SCHEMBL19233196 | 0.82 | BRAF (0.58) | BRAFKDR | |
| SCHEMBL20725655 | 0.82 | BRAF (0.54) | BRAFKDR | |
| SCHEMBL20725664 | 0.81 | BRAF (0.51) | BRAFKDR | |
| SCHEMBL16139200 | 0.81 | BRAF (0.67) | BRAF | |
| SCHEMBL20725636 | 0.79 | KDR (0.57) | BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780341-B1 | KINASE MODULATING COMPOUNDS, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2019-02-13 | — | — | EP | disclosed |