Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15638673 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL31338794 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL663207 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL28695900 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL5495726 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL196200 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL25252646 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL9787863 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL22263515 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 | |
| SCHEMBL27697767 | 1.00 | TSHR (0.48) | TSHROPRM1SPHK1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261557-A | Cyclic cyanoketene derivatives as KEAP1 modulators | 默沙东有限责任公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-3441382-A1 | OXA ACID COMPOUND | Moresco Corporation (JP) | 2019-02-13 | — | — | EP | disclosed |