SCHEMBL663207

SCHEMBL663207

CCCCCCC(C)C#N

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
OPRM1 P35372 1/20 0.44
SPHK1 Q9NYA1 1/20 0.41
LMNA P02545 1/20 0.41
DNM1 Q05193 2/20 0.40
THRB P10828 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
ACE2 Q9BYF1 1/20 0.38
GPR84 Q9NQS5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15638673 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL31338794 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL28695900 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL5495726 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL196200 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL25252646 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL9787863 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL20725833 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL22263515 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1
SCHEMBL27697767 1.00 TSHR (0.48) TSHROPRM1SPHK1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024017178-A1 SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS AVITAR BIOSCIENCES, INC. (CN) 2024-01-25 WO claimed
EP-4074807-B1 COMPOSITIONS COMPRISING A FLUOROOLEFIN CHEMOURS CO FC LLC (US) 2025-07-09 EP disclosed
EP-3543310-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-32 CHEMOURS CO FC LLC (US) 2024-07-03 EP disclosed
EP-3299435-B1 METHOD OF PREPARING A COMPOSITION COMPRISING HFC-1234YF CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
CN-115605480-B Sulfonylamide-substituted compounds and their use as beta-lactamase inhibitors 宁夏农林科学院 2024-04-05 CN disclosed
CN-117683029-A Bcl-2 inhibitors 百济神州有限公司 2024-03-12 CN disclosed
EP-3309233-B2 COMPOSITIONS COMPRISING HFC-1234YF AND HFC-152A CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
EP-2749623-B2 Method for replacing a high GWP refrigerant in a refrigeration, air-conditioning, or heat pump apparatus CHEMOURS CO FC LLC (US) 2024-02-21 EP disclosed
CN-113845884-B Compositions comprising fluoroolefins 科慕埃弗西有限公司 2024-02-02 CN disclosed
WO-2024017178-A1 SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS AVITAR BIOSCIENCES, INC. (CN) 2024-01-25 WO disclosed
WO-2002046328-A2 REFRIGERANT COMPOSITIONS CONTAINING A COMPATIBILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-13 WO disclosed
EP-1171416-A1 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY LIMITED (GB) 2002-01-16 EP disclosed
WO-2000061539-A1 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY LIMITED (GB) 2000-10-19 WO disclosed
EP-0792259-B1 CATALYZED VAPOR PHASE HYDROCYANATION OF DIOLEFINIC COMPOUNDS DU PONT (US) 1999-08-04 EP disclosed
EP-0792259-A1 CATALYZED VAPOR PHASE HYDROCYANATION OF DIOLEFINIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-03 EP disclosed
WO-1996016022-A1 CATALYZED VAPOR PHASE HYDROCYANATION OF DIOLEFINIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-30 WO disclosed
US-5449807-A Using complex of zero-valent nickel and bidentate phosphate ligand as catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-12 US disclosed
EP-0267136-B1 QUATERNARY AMMONIUM SALTS USED AS PHASE TRANSFER CATALYSTS ALTER, S.A. (ES) 1990-09-19 EP disclosed
EP-0267136-A2 Quaternary ammonium salts used as phase transfer catalysts ALTER, S.A. (ES) 1988-05-11 EP disclosed
US-4098806-A PROCESS FOR FUNCTIONALIZING PERFLUOROHALOGENOALKANES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-04 US disclosed