Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.80 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.64 |
| ▸ | ABL1 | P00519 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | PRKDC | P78527 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HCK | P08631 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884073 | 0.95 | PIK3CG (0.82) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884092 | 0.94 | PIK3CG (0.80) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884087 | 0.93 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884082 | 0.92 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884110 | 0.92 | PIK3CG (0.79) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884089 | 0.92 | PIK3CG (0.81) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884074 | 0.92 | PIK3CG (0.83) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884094 | 0.91 | PIK3CD (0.78) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL9884124 | 0.90 | PIK3CG (0.74) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 | |
| SCHEMBL20725919 | 0.90 | PIK3CD (0.65) | PIK3CGPIK3CDPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441392-A1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Intellikine, LLC (US) | 2019-02-13 | — | — | EP | disclosed |