Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.57 |
| ▸ | PRKDC | P78527 | 5/20 | 0.56 |
| ▸ | ABL1 | P00519 | 4/20 | 0.56 |
| ▸ | SRC | P12931 | 4/20 | 0.56 |
| ▸ | MTOR | P42345 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | HCK | P08631 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18708596 | 0.92 | PIK3CG (0.66) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884211 | 0.91 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL20725918 | 0.90 | PIK3CG (0.80) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL19418809 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884212 | 0.87 | PIK3CD (0.86) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9883994 | 0.86 | PIK3CG (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL16241639 | 0.86 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL18708793 | 0.86 | PIK3CG (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884289 | 0.86 | PIK3CG (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884301 | 0.86 | PIK3CG (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441392-A1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Intellikine, LLC (US) | 2019-02-13 | — | — | EP | disclosed |