Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.58 |
| ▸ | CCR3 | P51677 | 7/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061536 | 0.85 | HPGDS (0.61) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2070963 | 0.83 | HPGDS (0.62) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL13610005 | 0.81 | HPGDS (0.75) | HPGDSMCHR1DRD2DRD4PRKAB2 | |
| SCHEMBL2071856 | 0.81 | HPGDS (0.69) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2071799 | 0.81 | HPGDS (0.71) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2073286 | 0.80 | HPGDS (0.68) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2071454 | 0.80 | HPGDS (0.70) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2070489 | 0.80 | HPGDS (0.73) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2069994 | 0.80 | HPGDS (0.65) | HPGDSCCR3MCHR1DRD2DRD4 | |
| SCHEMBL2072461 | 0.80 | HPGDS (0.65) | HPGDSCCR3MCHR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902373-B2 | asthma; for treating prostaglandin D2 mediated diseases; e.g. 6-(3-fluorophenyl)-N-[1-(1-methyl-1H-tetrazol-5-yl)piperidin-4-yl]nicotinamide | PFIZER INC (US) | 2011-03-08 | — | — | US | disclosed |