Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.65 |
| ▸ | MAOA | P21397 | 16/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.59 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520095 | 0.83 | MAOA (0.79) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL3190402 | 0.82 | MAOA (0.69) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL28493544 | 0.81 | MAOA (0.55) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL28500675 | 0.80 | DYRK1A (0.64) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL18212310 | 0.79 | MAOA (0.64) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL16892263 | 0.79 | MAOA (0.64) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL23175614 | 0.79 | DYRK1A (1.00) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL13874913 | 0.78 | MAOA (0.74) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL3848233 | 0.78 | MAOA (0.82) | DYRK1AMAOAKDM4EDYRK3CCNT1 | |
| SCHEMBL28491520 | 0.78 | MAOA (0.55) | DYRK1AMAOAKDM4EDYRK3CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091015-B1 | BETA-CARBOLINE, DIHYDRO-BETA-CARBOLINE AND TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES AND METHOD FOR PREPARING SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, FUNGICIDES AND INSECTICIDES | UNIV NANKAI (CN) | 2019-02-13 | — | — | EP | disclosed |