Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894736 | 0.85 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5701640 | 0.81 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7586895 | 0.80 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6652511 | 0.80 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL247231 | 0.78 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16070946 | 0.77 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21811060 | 0.77 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL13043000 | 0.76 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL13343088 | 0.76 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10934218 | 0.75 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173826-B1 | HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION | PEGAVISION CORP (TW) | 2019-02-13 | — | — | EP | disclosed |