Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586895 | 0.95 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15497553 | 0.86 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL20726541 | 0.85 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL12313569 | 0.84 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3622054 | 0.83 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11986800 | 0.83 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6652511 | 0.83 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15355902 | 0.82 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15355910 | 0.82 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15355891 | 0.82 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730767-B2 | OPTICAL TRANSPARENT; BIOCOMPATIBLE MEDICAL EQUIPMENT | BAUSCH & LOMB INCORPORATED | 2004-05-04 | — | — | US | disclosed |