Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 4/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127212 | 0.90 | POLB (0.41) | POLBDHPSCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL16038432 | 0.89 | POLB (0.46) | POLBDHPSCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL16075447 | 0.83 | CHRNA7 (0.46) | DHPSCYP1A1CYP1A2CYP1B1FPR2 | |
| SCHEMBL1396987 | 0.82 | DHPS (0.51) | DHPSCYP1A1CYP1A2CYP1B1CSNK2A1 | |
| SCHEMBL16075514 | 0.82 | DHPS (0.53) | DHPSCYP1A1CYP1A2CYP1B1DPP4 | |
| SCHEMBL16075419 | 0.81 | DHPS (0.52) | DHPSCYP1A1CYP1A2CYP1B1MEN1 | |
| SCHEMBL1397030 | 0.81 | DHPS (0.54) | POLBDHPSDPP4MEN1KMT2A | |
| SCHEMBL16075438 | 0.81 | DHPS (0.52) | DHPSCYP1A1CYP1A2CYP1B1DPP4 | |
| SCHEMBL1396924 | 0.80 | DPP4 (0.44) | DHPSDPP4FPR2IKBKBMAP4K4 | |
| SCHEMBL16075403 | 0.78 | MAP4K4 (0.43) | DHPSFPR2MAP4K4ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440938-A1 | 4-AMINO-6-(4-SUBSTITUTED-PHENYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2019-02-13 | — | — | EP | disclosed |