Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CASP2 | P42575 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421683 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP1A2CYP2C19MAPTCYP2C9 | |
| SCHEMBL8048986 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2CYP2C19MAPTCYP2C9 | |
| SCHEMBL4419515 | 0.82 | FAAH (0.39) | SMN1; SMN2KMT2AMEN1MAPTTSHR | |
| SCHEMBL20733272 | 0.80 | PIK3CD (0.44) | SMN1; SMN2KMT2ACASP2CA12F13A1 | |
| SCHEMBL1446337 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP1A2CYP2C19MAPTCYP2C9 | |
| SCHEMBL20733275 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL12385867 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL259671 | 0.77 | ACE2 (0.47) | KMT2ACA12CYP1A2CA6CA7 | |
| SCHEMBL4467977 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL22662832 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ACYP1A2MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-11-19 | — | — | US | disclosed |
| WO-2019030197-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | HRH3, HRH4, HRH1 | SMN1; SMN2 4684/4885KMT2A 2885/4885CASP2 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.