SCHEMBL20733334

SCHEMBL20733334

Cl/C=C1\C=C(c2ccccc2)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.47
PTPRC P08575 4/20 0.47
PTPRF P10586 2/20 0.47
CDC25B P30305 2/20 0.47
BACE1 P56817 5/20 0.39
ALDH1A1 P00352 4/20 0.37
CYP2A6 P11509 1/20 0.37
MAPK1 P28482 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HSD17B3 P37058 1/20 0.34
HSD17B10 Q99714 2/20 0.32
HPGD P15428 1/20 0.32
BCL2L1 Q07817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18519818 1.00 PTPN1 (0.47) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL8463710 0.78 HTR6 (0.46) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL29713644 0.71 PTPN1 (0.47) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL24449746 0.68 PTPN1 (0.37) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL19252765 0.67 PTPN1 (0.52) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL30433091 0.67 PTPN1 (0.76) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL25784565 0.67 PTPN1 (0.52) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL5087342 0.67 PTPN1 (0.52) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL30930003 0.67 PTPN1 (0.52) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL5139479 0.67 PTPN1 (0.76) PTPN1PTPRCPTPRFCDC25BBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132665-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2020-06-25 WO disclosed
WO-2019147878-A1 POLYCYCLOOLEFIN MONOMERS AND CATALYST ACTIVATED BY COMPOUND CAPABLE OF GENERATING PHOTOACID AS OPTICAL MATERIALS PROMERUS, LLC (US) 2019-08-01 WO disclosed
WO-2019032937-A1 POLYCYCLOOLEFIN POLYMER AND INORGANIC NANOPARTICLE COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2019-02-14 WO disclosed