Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 15/20 | 0.70 |
| ▸ | PRMT5 | O14744 | 13/20 | 0.70 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199739 | 1.00 | METTL3 (0.70) | METTL3PRMT5WDR77 | |
| SCHEMBL23469007 | 0.91 | PRMT5 (0.67) | METTL3PRMT5WDR77 | |
| SCHEMBL23892716 | 0.87 | METTL3 (0.66) | METTL3PRMT5WDR77 | |
| SCHEMBL22002309 | 0.87 | METTL3 (0.66) | METTL3PRMT5WDR77 | |
| SCHEMBL23469010 | 0.87 | PRMT5 (0.59) | METTL3PRMT5WDR77 | |
| SCHEMBL23469018 | 0.87 | PRMT5 (0.59) | METTL3PRMT5WDR77 | |
| SCHEMBL23544713 | 0.87 | PRMT5 (0.64) | METTL3PRMT5WDR77 | |
| SCHEMBL24380380 | 0.86 | METTL3 (0.63) | METTL3PRMT5WDR77 | |
| SCHEMBL23892710 | 0.85 | METTL3 (0.65) | METTL3PRMT5WDR77 | |
| SCHEMBL18571654 | 0.85 | METTL3 (0.65) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032859-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2019-02-14 | — | — | WO | disclosed |