Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205387 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| SCHEMBL28341435 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| SCHEMBL6506788 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| SCHEMBL6506197 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| SCHEMBL60452 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| SCHEMBL18180403 | 1.00 | HRH3 (0.65) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| Butane SCHEMBL2507294 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| Hydrochloric Acid SCHEMBL15141354 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| Water SCHEMBL28467820 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 | |
| Ammonia Solution, Strong SCHEMBL8765175 | 0.97 | HRH3 (0.62) | HRH3CYP1A2MAPK1SMN1; SMN2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623361-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2020-03-18 | — | — | EP | disclosed |
| US-20190047997-A1 | 6,7,8,9-TETRAHYDRO-5H-PYRIDO[2,3-d]AZEPINE DOPAMINE D3 LIGANDS | PFIZER INC. (US) | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047997-A1 | 6,7,8,9-TETRAHYDRO-5H-PYRIDO[2,3-d]AZEPINE DOPAMINE D3 LIGANDS | DRD3, DRD2, DRD4 | HRH3 160/4885CYP1A2 215/4885MAPK1 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.