Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 13/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 13/20 | 0.55 |
| ▸ | FGFR3 | P22607 | 12/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886719 | 1.00 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733916 | 0.92 | FGFR1 (0.49) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733904 | 0.91 | FGFR1 (0.47) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL28378571 | 0.90 | FGFR1 (0.59) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733952 | 0.89 | FGFR1 (0.53) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733985 | 0.89 | FGFR1 (0.58) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29545913 | 0.89 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29546411 | 0.89 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL5391527 | 0.87 | FGFR1 (0.71) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29886181 | 0.87 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019029541-A1 | FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-02-14 | — | — | WO | disclosed |