Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 12/20 | 0.59 |
| ▸ | FGFR4 | P22455 | 12/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886719 | 0.90 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733938 | 0.90 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL4402953 | 0.86 | FGFR1 (0.76) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL28380121 | 0.86 | FGFR1 (0.60) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733916 | 0.83 | FGFR1 (0.49) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733904 | 0.81 | FGFR1 (0.47) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29545913 | 0.80 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29546411 | 0.80 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL28373856 | 0.80 | FGFR1 (0.67) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL15434046 | 0.80 | FGFR4 (0.60) | FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809576-B | FGFR kinase inhibitor and pharmaceutical use | 奥克兰联合服务有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110809576-A | FGFR kinase inhibitor and pharmaceutical use | 奥克兰联合服务有限公司 | 2020-02-18 | — | — | CN | disclosed |