SCHEMBL20734765

SCHEMBL20734765

COc1cc(NC(=O)CC(C)S)c2ncccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.61
MEN1 O00255 5/20 0.58
ALDH1A1 P00352 5/20 0.57
HDAC6 Q9UBN7 3/20 0.57
HTT P42858 2/20 0.57
HDAC1 Q13547 2/20 0.55
HDAC8 Q9BY41 1/20 0.55
HSP90AA1 P07900 4/20 0.54
HSP90AB1 P08238 4/20 0.54
IDO1 P14902 1/20 0.54
MAPT P10636 3/20 0.53
HPGD P15428 2/20 0.53
TP53 P04637 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HSD17B10 Q99714 1/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 2/20 0.53
KDM4E B2RXH2 3/20 0.53
CYP1A2 P05177 2/20 0.53
CASP1 P29466 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923441 0.86 KMT2A (0.67) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL8402851 0.84 KMT2A (0.68) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL22556212 0.80 KMT2A (0.73) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL21149303 0.80 KMT2A (0.73) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL29558933 0.80 KMT2A (0.73) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL8856110 0.80 KMT2A (0.73) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL18257167 0.78 KMT2A (0.77) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL8117024 0.77 KMT2A (0.68) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL23645085 0.76 ALDH1A1 (0.62) KMT2AMEN1ALDH1A1HDAC6HTT
SCHEMBL28468186 0.76 KMT2A (0.86) KMT2AMEN1ALDH1A1HDAC6HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10675842-B2 Transparent electrode and organic electronic device including the same Konica Minolta, Inc. (JP) 2020-06-09 US disclosed
US-20190047258-A1 TRANSPARENT ELECTRODE AND ORGANIC ELECTRONIC DEVICE INCLUDING THE SAME MERCK PATENT GMBH (DE) 2019-02-14 US disclosed