Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734815 | 1.00 | MAOB (0.36) | MAOBMAOAAPPNR4A2HPGD | |
| SCHEMBL24333339 | 0.84 | MAOB (0.37) | MAOBAPPMEN1KMT2A | |
| SCHEMBL20735040 | 0.82 | SMN1; SMN2 (0.37) | MAOBMAOAKMT2A | |
| SCHEMBL20734938 | 0.82 | SMN1; SMN2 (0.37) | MAOBMAOAKMT2A | |
| SCHEMBL20734863 | 0.80 | MAOB (0.35) | MAOBMAOAAPPNR4A2OPRM1 | |
| SCHEMBL20735047 | 0.79 | NPSR1 (0.40) | MAOBMAOANR4A2MEN1KMT2A | |
| SCHEMBL20734933 | 0.79 | NPSR1 (0.40) | MAOBMAOANR4A2MEN1KMT2A | |
| SCHEMBL20734860 | 0.79 | FFAR1 (0.44) | MAOBMAOAAPPKMT2A | |
| SCHEMBL20734861 | 0.79 | FFAR1 (0.44) | MAOBMAOAAPPKMT2A | |
| SCHEMBL24333167 | 0.78 | MAOB (0.33) | MAOBMAOAAPPNR4A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019029273-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京卓凯生物技术有限公司 | 2019-02-14 | — | — | WO | disclosed |
| WO-2019029274-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND AND PREPARATION METHOD THEREFOR | 北京卓凯生物技术有限公司 | 2019-02-14 | — | — | WO | disclosed |