Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734815 | 0.84 | MAOB (0.36) | MAOBAPPMEN1KMT2A | |
| SCHEMBL20734816 | 0.84 | MAOB (0.36) | MAOBAPPMEN1KMT2A | |
| SCHEMBL24333202 | 0.68 | ALDH1A1 (0.39) | MAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL20735040 | 0.67 | SMN1; SMN2 (0.37) | MAOBKMT2ASLC6A3ALDH1A1 | |
| SCHEMBL20734938 | 0.67 | SMN1; SMN2 (0.37) | MAOBKMT2ASLC6A3ALDH1A1 | |
| SCHEMBL21973638 | 0.67 | P2RX7 (0.46) | MAOBIDO1AGXT | |
| SCHEMBL21973405 | 0.67 | CYP1A2 (0.44) | MEN1KMT2ASLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL21929344 | 0.66 | MAOB (0.40) | MAOBHTR1AAGXTALDH1A1MPO | |
| SCHEMBL20734860 | 0.66 | FFAR1 (0.44) | MAOBAPPKMT2AFFAR1ALDH1A1 | |
| SCHEMBL20734861 | 0.66 | FFAR1 (0.44) | MAOBAPPKMT2AFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647306-B1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND AND PREPARATION METHOD THEREFOR | BEIJING JOEKAI BIOTECH LLC (CN) | 2022-04-06 | — | — | EP | disclosed |