SCHEMBL20735271

SCHEMBL20735271

CC(C)=CCCC(C)CC(=O)OCCO

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.57
ALDH1A1 P00352 2/20 0.53
GGPS1 O95749 2/20 0.41
FDPS P14324 2/20 0.41
EPHX2 P34913 1/20 0.39
USP2 O75604 1/20 0.38
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
STAT3 P40763 1/20 0.37
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23707013 0.92 ALOX15 (0.62) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL20735116 0.91 ALOX15 (0.54) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL20734973 0.89 ALOX15 (0.53) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL15727370 0.89 ALOX15 (0.73) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL13176163 0.89 ALOX15 (0.73) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL28889041 0.88 ALOX15 (0.51) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL19919333 0.87 ALOX15 (0.57) ALOX15ALDH1A1GGPS1FDPSEPHX2
SCHEMBL29447136 0.84 ALOX15 (0.54) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL29447137 0.84 ALOX15 (0.54) ALOX15ALDH1A1GGPS1FDPSTSHR
SCHEMBL20734974 0.83 ALOX15 (0.56) ALOX15ALDH1A1GGPS1FDPSUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174457-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2023-06-08 US claimed
US-20240391864-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2024-11-28 US disclosed
EP-4382518-A2 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF Iowa State University Research Foundation, Inc. (US) 2024-06-12 EP disclosed
EP-3503733-B1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2024-03-20 EP disclosed
US-20230174457-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2023-06-08 US disclosed
US-20230174457-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2023-06-08 US disclosed
US-20230174457-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF UNIV IOWA STATE RES FOUND INC (US) 2023-06-08 US disclosed
US-11485701-B2 Insect repellent compounds and compositions, and methods thereof IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-11-01 US disclosed
US-11485701-B2 Insect repellent compounds and compositions, and methods thereof IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-11-01 US disclosed
US-20190047937-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485701-B2 Insect repellent compounds and compositions, and methods thereof C5, CYP51A1, DDT ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885
US-20190047937-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF C5, CYP51A1, DDT ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885
US-20230174457-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF C5, CYP51A1, DDT ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885
US-20240391864-A1 INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF C5, CYP51A1, DDT ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.