SCHEMBL20735952

SCHEMBL20735952

Cc1nc2ccccc2n1-c1cccc(-c2ccc3c4c(ccc3c2)-c2cc3ccccc3cc2C42c3ccccc3-c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
ALDH1A1 P00352 1/20 0.34
MAPK10 P53779 2/20 0.34
CYP1A2 P05177 1/20 0.34
PDE10A Q9Y233 1/20 0.34
HSD11B1 P28845 1/20 0.34
PIK3CD O00329 2/20 0.33
PIK3CA P42336 2/20 0.33
MTOR P42345 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.32
GSR P00390 1/20 0.32
THRB P10828 1/20 0.32
FLT3 P36888 1/20 0.31
MET P08581 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20737316 0.95 MAPK1 (0.40) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL20737752 0.94 MAPK1 (0.41) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL20737118 0.92 MAPK1 (0.43) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL20735953 0.91 ESR1 (0.39) MAPK1HTTALDH1A1MAPK10PDE10A
SCHEMBL20736522 0.91 MAPK1 (0.45) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL20735956 0.90 PDE10A (0.37) ALDH1A1MAPK10CYP1A2PDE10AGSR
SCHEMBL20735936 0.89 MAPK1 (0.40) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL27250573 0.88 MAPK1 (0.39) MAPK1HTTNR1H2NR1H3ALDH1A1
SCHEMBL20737110 0.87 ESR1 (0.39) MAPK1HTTMAPK10
SCHEMBL20735955 0.87 PDE10A (0.39) MAPK10CYP1A2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885NR1H2 1798/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885NR1H2 1798/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPK1 499/4885HTT 2278/4885NR1H2 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.