SCHEMBL20736552

SCHEMBL20736552

CCCn1c(-c2cccc(-c3ccc4cc5c(cc4c3)C3(c4ccccc4-c4ccccc43)c3cc4ccccc4cc3-5)c2)nc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
KDM4E B2RXH2 8/20 0.49
ALDH1A1 P00352 5/20 0.49
LMNA P02545 3/20 0.49
TSHR P16473 3/20 0.49
GAA P10253 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TP53 P04637 5/20 0.48
SMN1; SMN2 Q16637 2/20 0.42
CYP11B1 P15538 1/20 0.42
HSD17B10 Q99714 4/20 0.40
HPGD P15428 3/20 0.40
GRM5 P41594 2/20 0.40
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20737720 0.94 KDM4E (0.54) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20736553 0.92 KDM4E (0.49) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20737744 0.92 MAPT (0.48) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL27250537 0.91 MAPT (0.47) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20737113 0.91 MAPT (0.48) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20736327 0.89 MAPT (0.48) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20736548 0.87 KDM4E (0.47) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20736555 0.87 KDM4E (0.46) MAPTKDM4EALDH1A1LMNAGAA
SCHEMBL20737742 0.86 KDM4E (0.48) MAPTKDM4EALDH1A1LMNATSHR
SCHEMBL20737719 0.86 KDM4E (0.54) MAPTKDM4EALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022728-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-06-25 US disclosed
US-11552251-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552251-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPT 1713/4885KDM4E 2169/4885ALDH1A1 125/4885
US-20190051835-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, ESR1, LEF1 MAPT 1713/4885KDM4E 2169/4885ALDH1A1 125/4885
US-12022728-B2 Organic electroluminescent element and electronic device L1CAM, ESR1, LEF1 MAPT 1713/4885KDM4E 2169/4885ALDH1A1 125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.