SCHEMBL207377

SCHEMBL207377

C=C(C)C(=O)OCC1=CCC(C(=C)C)CC1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.59
ALDH1A1 P00352 2/20 0.59
CYP1B1 Q16678 1/20 0.59
TSHR P16473 3/20 0.53
MAPK1 P28482 1/20 0.53
LMNA P02545 2/20 0.50
KDM4E B2RXH2 1/20 0.47
TRPA1 O75762 1/20 0.47
RAB9A P51151 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MGMT P16455 1/20 0.45
CES2 O00748 1/20 0.39
TRPV1 Q8NER1 1/20 0.38
PTPN1 P18031 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16002382 0.88 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL1302136 0.88 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL20214186 0.87 ALOX15 (0.54) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL20213683 0.87 ALOX15 (0.54) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL17522709 0.86 ALOX15 (0.59) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL16774726 0.86 ALOX15 (0.59) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL19919386 0.86 ALOX15 (0.62) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL10081724 0.86 ALOX15 (0.59) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL19919387 0.84 ALOX15 (0.57) ALOX15ALDH1A1CYP1B1TSHRMAPK1
SCHEMBL19919412 0.83 ALOX15 (0.60) ALOX15ALDH1A1CYP1B1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799885-B2 Photo or electron beam curable compositions CORNING INCORPORATED (US) 2010-09-21 US claimed
US-20080269448-A1 Photo or electron beam curable compositions CORNING INCORPORATED 2008-10-30 US claimed
WO-2008051233-A2 PHOTO OR ELECTRON BEAM CURABLE COMPOSITIONS CORNING INCORPORATED (US) 2008-05-02 WO claimed
US-20190233556-A1 HIGH REFRACTIVE INDEX POLYMERIZABLE MONOMERS AND APPLICATIONS THEREOF CORNING INCORPORATED (US) 2019-08-01 US disclosed
WO-2018075848-A1 HIGH REFRACTIVE INDEX POLYMERIZABLE MONOMERS AND APPLICATIONS THEREOF CORNING INCORPORATED (US) 2018-04-26 WO disclosed
US-8557941-B2 Photo or electron beam curable compositions CORNING INCORPORATED (US) 2013-10-15 US disclosed
EP-2576172-A1 REPLICATION METHOD Corning Incorporated (US) 2013-04-10 EP disclosed
US-20120068112-A1 PHOTO OR ELECTRON BEAM CURABLE COMPOSITIONS SHUSTACK PAUL J (US) 2012-03-22 US disclosed
US-8088877-B2 Photo or electron beam curable compositions CORNING INCORPORATED (US) 2012-01-03 US disclosed
WO-2011149803-A1 REPLICATION METHOD CORNING INCORPORATED (US) 2011-12-01 WO disclosed
US-20110291330-A1 REPLICATION METHOD AND ARTICLES OF THE METHOD CORNING INCORPORATED 2011-12-01 US disclosed
US-7799885-B2 Photo or electron beam curable compositions CORNING INCORPORATED (US) 2010-09-21 US disclosed
US-20090170726-A1 PHOTO OR ELECTRON BEAM CURABLE COMPOSITIONS SHUSTACK PAUL J 2009-07-02 US disclosed
US-20080269448-A1 Photo or electron beam curable compositions CORNING INCORPORATED 2008-10-30 US disclosed
WO-2008051233-A2 PHOTO OR ELECTRON BEAM CURABLE COMPOSITIONS CORNING INCORPORATED (US) 2008-05-02 WO disclosed