Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27400354 | 0.89 | TUBB1 (0.55) | TUBB1 | |
| SCHEMBL26606683 | 0.88 | TUBB1 (0.46) | TUBB1 | |
| SCHEMBL24360630 | 0.86 | TUBB1 (0.53) | TUBB1 | |
| SCHEMBL22315771 | 0.85 | TUBB1 (0.46) | TUBB1 | |
| SCHEMBL20738968 | 0.85 | TUBB1 (0.42) | TUBB1 | |
| SCHEMBL22308454 | 0.84 | TUBB1 (0.43) | TUBB1 | |
| SCHEMBL20732247 | 0.83 | TUBB1 (0.59) | TUBB1 | |
| SCHEMBL24360595 | 0.81 | TUBB1 (0.64) | TUBB1 | |
| SCHEMBL26606748 | 0.79 | TUBB1 (0.35) | TUBB1 | |
| SCHEMBL20732280 | 0.78 | TUBB1 (0.57) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019031615-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | 大日本住友製薬株式会社 | 2019-02-14 | — | — | WO | disclosed |