Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.59 |
| ▸ | Q9HBH1 | 2/20 | 0.32 | |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57601 | 0.93 | TUBB1 (0.61) | TUBB1PDFDPP4 | |
| SCHEMBL27400344 | 0.84 | TUBB1 (0.51) | TUBB1PDFDPP4 | |
| SCHEMBL88548 | 0.84 | TUBB1 (0.74) | TUBB1PDF | |
| SCHEMBL13660108 | 0.84 | TUBB1 (0.74) | TUBB1PDF | |
| SCHEMBL58085 | 0.84 | TUBB1 (0.74) | TUBB1PDF | |
| SCHEMBL6673500 | 0.84 | TUBB1 (0.64) | TUBB1 | |
| SCHEMBL6674144 | 0.84 | TUBB1 (0.64) | TUBB1 | |
| SCHEMBL15434851 | 0.83 | TUBB1 (0.67) | TUBB1PDF | |
| SCHEMBL26606699 | 0.83 | TUBB1 (0.61) | TUBB1PDF | |
| SCHEMBL20738967 | 0.83 | TUBB1 (0.45) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |
| WO-2019031614-A1 | ANTIBODY-DRUG CONJUGATES INCLUDING HEMIASTERLIN DERIVATIVE | 大日本住友製薬株式会社 | 2019-02-14 | — | — | WO | disclosed |