Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550852 | 0.81 | RAB9A (0.48) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL23790725 | 0.79 | RAB9A (0.43) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL21205742 | 0.79 | RAB9A (0.43) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL20468205 | 0.79 | RAB9A (0.43) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL18914923 | 0.78 | RAB9A (0.42) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL20468136 | 0.77 | RAB9A (0.41) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL18881076 | 0.77 | GAA (0.41) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL20902085 | 0.76 | GAA (0.43) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL18474054 | 0.76 | RAB9A (0.41) | RAB9ANPC1TP53SMN1; SMN2TSHR | |
| SCHEMBL19968631 | 0.75 | RAB9A (0.45) | RAB9ANPC1TP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032631-A1 | OXIME ETHER COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-02-14 | — | — | WO | disclosed |