Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323237 | 0.90 | — | — | |
| SCHEMBL28723687 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL20171986 | 0.75 | — | — | |
| SCHEMBL28490646 | 0.73 | SSTR4 (0.34) | — | |
| SCHEMBL31416574 | 0.70 | SSTR4 (0.31) | — | |
| SCHEMBL29956694 | 0.68 | MAPK1 (0.32) | — | |
| SCHEMBL16053677 | 0.67 | — | — | |
| SCHEMBL19857578 | 0.67 | COMT (0.35) | COMTHTT | |
| SCHEMBL25756645 | 0.67 | S1PR1 (0.32) | COMT | |
| SCHEMBL18420206 | 0.65 | SSTR4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668873-A1 | IMIDAZO[1,2-A]IMIDAZOL-2-ONE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS PARKINSON'S DISEASE | H. Hoffnabb-La Roche Ag (CH) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034713-A1 | IMIDAZO[1,2-A]IMIDAZOL-2-ONE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS PARKINSON'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2019-02-21 | — | — | WO | disclosed |