Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | PYGB | P11216 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612320 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL19738683 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL7147741 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL2621548 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL15215701 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL13879350 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL15621594 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL15061687 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL21847893 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR | |
| SCHEMBL16946217 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MAPTLGALS8GAATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668502-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | AbbVie Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019035927-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC. (US) | 2019-02-21 | — | — | WO | disclosed |